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This finding was supported by the study of Tilton et al
Kopetz S , Grothey A, Yaeger R, Cuyle PA, Huijberts S, M Schellens JH, Elez E, Fakih M, Viladot CM, Peeters M, Desai J, Yoshino T, Ciardiello F, Wasan HS, Maharry K, Christy-Bittel J, Gollerkeri A, Cutsem EV, Tabernero J
Consistent with this finding, RVX combated apoptosis in the myocardial ischemia rat model 60
This limits the ability to correctly attribute an observed biologic effect to a specific mitochondrial genotype (or mito-nuclear interaction)
Sun W, Zhang L, Lu X, Feng L, Sun S
