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This binding switches 15LO1s preferred substrate from free arachidonic acid to arachidonic acid conjugated to PE, which generates ferroptotic lipids, including the hydroperoxy-phospholipid 15-hydroperoxy-eicosatetraenoic acidPE (15-HpETE-PE) (6, 7, 10, 13)

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on MDA-MB-231 breast cancer cells demonstrated the ability of cardamonin to facilitate programmed cell death induced by reactive oxygen species (ROS) through HIF-1a signaling [165]

This protein-bound glutathione may be deposited in the liver, attenuating hepatitis

Statistical Analyses An a priori power analysis was conducted using G*Power version 3.1.9.7 (Dsseldorf, Germany), following the use of the data involving three participants in each group who completed this study