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doi: 10.1152/ajpgi.00048.2015
In cell culture models of human macrophage foam cells, the inability to clear cholesterol from macrophages with compromised lysosome function continues even in the presence of compounds that stimulate efflux (161,163)
However, current evidence is mostly from observational or single-model experiments, lacking systematic cross-tissue validation
When selecting supplements, look for products with third-party quality verification such as USP Verified or NSF Certified to ensure purity and accurate labeling
