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One research group proposed that ROS are a signal generated by ER stress and UPR activation, consistent with their observation that antioxidant treatment reduces oxidative stress and UPR activation [41]

Clinical trials have reported good tolerability even at doses up to 812 g/day
doi: 10.1093/nar/gky006 91 SterlinDVelascoGMoshousDTouzotFMahlaouiNet al

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