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6 Conclusion The gut microbiota has emerged as a central player in thyroid health, exerting profound influence over immune regulation, nutrient absorption, and thyroid hormone metabolism

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Additionally, 4-hydroxy-nonenal (HNE) and Isoprostanes (F2-isoprostane, 15-(S)-8-isoprostagladin F2) are by-products of PUFA, and are also considered as indices of lipid peroxidation (33, 34)

Consequently, mitochondrial dysfunction facilitates a decrease in ATP production, Ca 2+ dyshomeostasis, and ROS generation

Thoroughly evaluate and address factors that can influence sex hormone levels, such as exposures to xenoestrogens, endocrine disruptors, and persistent organic pollutants
