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mBIO (2022) 13:0095122

Antibody-mediated immunity induced by engineered Escherichia coli OMVs carrying heterologous antigens in their lumen
3.2 Destruction of periodontal soft tissues The integrity and function of PDLFs, essential for softtissue homeostasis, are compromised by ferroptosis through a twofold assault on collagen: synthesis is reduced because PDLF viability and activity are impaired, while degradation is accelerated by ferroptosisassociated ROS and proinflammatory mediators ( in vitro primary cell models, indicate that ferroptosis in periodontal ligament fibroblasts serves as an active driver of soft tissue destruction

E., MacDonald A

Fatty acid synthase: an emerging target in cancer
