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Collectively, these data might indicate that the diminished ROS buffering of GSH-deficient cells leads to an increased activation of the mTOR pathway which could drive to the MZB-like properties of Gclc -deficient FoB
doi:10.1016/j.glmedi.2024.100081 5

As the body ages, glutathione levels typically decrease, which has been associated with increased oxidative damage and signs of ageing, particularly in the skin

Cell Stem Cell 21:569573
