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Finally, a significant negative effect on Lac-Rh activity was measured in ethyl acetate, hexane, and n-butyl acetate solvents, which is likely due to a rapid structural denaturation or disruption of the active site (Hemlata et al

Sancho-Shimizu V, Brodin P, Cobat A, et al

For the patients in this study, vulvar melanosis occurred on the labia minora (55 [43%]), on the labia majora (33 [26%]), on both the labia minora and the labia majora (19 [15%]), on the posterior fourchette (7 [5%]), on the vestibule (5 [4%]), and on the clitoris (2 [2%])

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[DOI] [PubMed] [Google Scholar] 22.Farid M., Demicco E.G., Garcia R., Ahn L., Merola P.R., Cioffi A., Maki R.G