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The topic has remained controversial

Recently, exercise-induced retinal neuroprotection has been reported [22]

[DOI] [PubMed] [Google Scholar] Dhar M

Taken together, our chemical proteomic, biochemical, and structural analyses identify GSTP1 as a prominent off-target of Molidustat and demonstrate direct inhibition of its enzymatic activity

However, the clinical use of DOX is limited due to the cumulative dose-related cardiotoxicity as a serious side effect, which results in arrhythmia, irreversible cardiomyopathy, and congestive heart failure (CHF) [1, 2]