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12 mg remains the highest-efficacy dose, but it carries a meaningfully worse GI burden and a correspondingly higher dropout risk

Compared to an injection, an oral tablet is more comfortable to take in many cases

doi: 10.1210/endo.143.7.8918 10 CowleyAWSzczepanska-SadowskaEStepniakowskiKMattsonD

Regular rotation of injection sites not only reduces the risk of joint pain and localized irritation but also helps maintain the integrity of the subcutaneous tissue, supporting the long-term success of tesamorelin therapy in research models

Before a deficiency, the skin tends to be dull, pale, or yellowish, a condition known as jaundice