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doi: 10.1210/endocr/bqaa204
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Furthermore, Nrf2 regulates the major NAD(P)H-generating enzyme, aldehyde dehydrogenase, via transcription, inducing aldehyde dehydrogenase expression in microsomes, the cytoplasm and mitochondria and generating NAD(P)H with the cofactor NAD(P) [102]
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It works by reducing oxidative stress and influencing melanin production, which can affect skin tone and clarity
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Cagrilintide is a long-acting amylin analogue that acts on amylin receptors in the hypothalamus and brainstem to regulate satiety, food intake, and gastric motility
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This structural change sets the stage for the profound functional alterations observed at the single-cell level, establishing a direct link between age-driven adipogenic conversion and a decline in the supportive capacity of the vascular niche
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