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Avoid use in epidural or spinal anesthesia

Our previous study (Li et al., 2017) revealed higher expression levels of NNMT in the toe extensor muscle, typically reliant on anaerobic energy metabolism for power generation, compared to the soleus muscle, typically reliant on aerobic energy metabolism

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Homocysteine : Also elevated when B12 or folate is low [*]

The process typically works as follows