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If you are lean and must use the thigh, always pinch the skin, use a 45-degree angle, and consider a shorter needle (3/8 inch instead of 1/2 inch) to reduce intramuscular injection risk

Spironolactone is often prescribed for acne, and it works to turn down androgen, a hormone that regulates oil production, and thus, reduces oil gland activity

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It is used in laboratory studies exploring tissue repair, cellular signaling, and regeneration pathways