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doi: 10.3390/nu12082428 [DOI] [PMC free article] [PubMed] [Google Scholar] 19.Marx W, Lane M, Hockey M, Aslam H, Berk M, Walder K, et al

doi:10.1007/s11239-015-1308-1 Chan NC, Weitz JI

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Figure 3 4.2 Necroptosis promotes antigen cross-presentation and durable immunity Restoration of necroptotic signaling in melanoma, either through epigenetic modifier inhibitors to reverse RIPK3/MLKL silencing or direct small-molecule activation of the RIPK1/RIPK3/MLKL axis, enhances tumor cell immunogenicity by amplifying DAMP release and antigen cross-presentation, a phenomenon that has been validated in both in vitro melanoma cell models and in vivo syngeneic melanoma mouse models (106)

Researchers tested patients with persistent IBS-like symptoms for mast cell activation syndrome (MCAS) and small intestine bacterial overgrowth (SIBO)