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These findings suggest that, although hyperglycemia and Cu dysregulation mutually exacerbate each other, correction of Cu imbalance by hypoglycemic drugs is not solely attributed to glucose-lowering effects but reflects distinct pharmacological properties

Incorporation of HTY into food products has been discussed for its antioxidant and anti-inflammatory properties, which are frequently linked with reduced oxidative stress and improved cardiovascular-related markers in experimental and dietary studies [6]

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Science 258 , 16501654 (1992)

215 Besides, excessive copper increases the expression of pyroptosis-related genes in jejunal epithelial cells, primarily through the activation of the ER stress pathway
