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doi: 10.1016/s0014-2999(02)01435-8
A 2015 study published in the Annals of Clinical and Laboratory Science found that intra-articular (injected into the joint) AOD-9604 enhanced cartilage regeneration in a rabbit model of knee osteoarthritis

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Injections are particularly good in these cases, as they bypass the tract for higher absorption rates than with food or oral supplements