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Animal evidence suggests this pathway also helps preserve lean mass during weight reduction, although the human data is still maturing

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Coll Relat Res 5(4):355368 Shoolingin-Jordan PM, Al-Daihan S, Alexeev D, Baxter RL, Bottomley SS, Kahari ID, Roy I, Sarwar M, Sawyer L, Wang SF (2003) 5-Aminolevulinic acid synthase: mechanism, mutations and medicine

When glucose metabolism is blocked or glycolysis is reduced, YAP/TAZ activity is decreased

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Shibata T., Yamada K., Watanabe M., Ikenaka K., Wada K., Tanaka K., Inoue Y
