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Some patients may require weekly injections initially, while others might transition to monthly doses as their levels stabilize

In particular, transsulfuration and remethylation pathways occurring in the kidney may be affected by renal disease

Groups 4, 5, 6, 7: These groups were received IP injection of vitamin B 12 at doses of 25, 50, 100 and 200 g kg -1 , respectively, for 10 consecutive days after surgically-induced crush injury in tibial nerve and served as crush plus vitamin B 12 groups

Optional ice: Apply cold pack to injection site for 30 to 60 seconds if you are prone to reactions Pinch: If lean, pinch a fold of skin at the injection site Insert: Quick, dart-like insertion at 90 degrees Inject: Slow, steady depression of plunger or pen button

Vitamin B12 injection 2