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A: Key biomarkers include body weight, fat mass, glucose and insulin levels, and markers related to NAD+ metabolism
This review will focus on the roles of NNMT in obesity and T2D, as it has been found that the expression of this methyltransferase is elevated in the white adipose tissue and liver of obese people and diabetic mice and that NNMT knockdown protects against diet-induced obesity and insulin resistance [11]
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