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The ability of probiotics to adhere to epithelial cells is a desirable characteristic of beneficial microorganisms allowing them to manifest their beneficial effects by persisting longer in the host GI tract (Collado et al., 2008

[DOI] [PMC free article] [PubMed] [Google Scholar] Metzler D.E

However, the last 30 years of AD research has been dominated by the amyloid hypothesis whereby the A peptide is putatively the central causative agent of a series of pathogenic events that ultimately leads to neurodegeneration (Frisoni et al., 2022)

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Inhibition of GPX4 activity leads to the accumulation of lipid peroxides, which triggers ferroptosis