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Non-selective MAO-I due to their side-effect/adverse reaction profile, like tranylcypromine have limited use in the treatment of depression in PD, while selective, reversible MAO-A inhibitors are recommended due to their easier clinical handling

Therefore, deficient OCM pathways lead to considerable neuronal damage and toxicity (Table 1)

Regulation of mycothiol metabolism by sigma(R) and the thiol redox sensor anti-sigma factor RsrA

38 , e120 (2023)

doi: 10.1038/s41591-018-0290-5 49 VelascoCRBrandlSMMelendezAVSchlaakAEBuschkyAPetersTet al
