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They reflect the processes of bone formation and resorption and can be used not only to diagnose metabolic bone disease and evaluate therapeutic effects but also to predict the rates of bone loss and fracture risk [39, 40]

Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles
At higher doses, H2S significantly reduced the rate and amplitude of cardiomyocyte action potential, while increasing the rate of repolarisation and significantly reduces pacemaker firing

Schwarz (70) found that the beneficial effects associated with fruit fiber vanished after adjusting for the healthy diet index
