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Patients with low B12 tend to catch more colds and recover more slowly

This effect can be completely reversed by SOD2 expression, indicating that hyperglycemia-induced OXTR suppression is due to hyperglycemia-induced consistent oxidative stress, which has been termed hyperglycemia memory ( in vivo study, which showed that OXTR expression was suppressed in many brain tissues, including the amygdala, hypothalamus and hippocampus, in prenatal diabetes exposure-induced offspring

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doi: 10.1248/bpb.b15-00133 [DOI] [PubMed] [Google Scholar] 22

Less than 1% of all subjects reported severe pain, and none of the participants reported grade 4 local adverse reactions