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evaluated AOD9604 in overweight and obese subjects, comparing various doses administered subcutaneously over 12 weeks

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In the control rats with a large lesion area and at the border of bone tissue and muscle, there was significant edema and no reaction of periosteum for mesenchymal stem cells (i.e., on post-operative day 2) (Figure 14)

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Guo, J., Hai, H., & Ma, Y