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MDSCs also produce reactive oxygen species (ROS) through NADPH oxidase, which directly impairs T cell function and contributes to the oxidative stress characteristic of the PC TME (141143)

doi: 10.1111/j.1346-8138.2006.00156.x

Takemura N, et al

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Clomipramine Treatment and Repeated Restraint Stress Alter Parameters of Oxidative Stress in Brain Regions of Male Rats
