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The bromodomain and extra-terminal (BET) inhibitors such as manoalide can suppress antioxidant genes (GPX2, ALDH3 A1, NRF2), inducing lethal ROS overload

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There are ample PRXs and GPXs present in the cytosol and mitochondria that convert H 2 O 2 or organic hydroperoxides, such as t -butyl hydroperoxide, to water or the corresponding alcohol

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sc-2004, Santa Cruz Biotechnology, Inc.) Half-area, black, round-bottom, polystyrene microplates (Cat

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