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Support Metabolism and Weight Management In cases of B12 deficiency, supplementation can help regulate metabolism, contributing to better energy conversion and even mild weight loss

Given that FOXO4 is a transcription factor, this nuclear translocation suggests increased transcriptional activity

The modulation of immune responses through vitamin D's effects on the innate and adaptive immune systems has made it a key factor in the regulation of periodontal health

Association Between IgA Deficiency & Other Autoimmune Conditions: A Population-Based Matched Cohort Study

While these functional improvements occurred in animal models, they suggest possible benefits for mobility and quality of life that would need confirmation in human trials