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FRDA fibroblasts treated with exogenous stress to induce the Nrf2 response indeed could not induce proper antioxidant compensation including upregulation of catalase, NQO1, and GST-P1 after t BHQ treatment or catalase, GST-P1, and SOD2 after oligomycin treatment
The third step in the cycle is the reduction of GSSSSG to regenerate GSSH
10.1016/j.yexcr.2017.10.034 269 WuF.YeH.LinJ.XuY.ZhangZ.XiongH.et al (2018a)
Roberts ADL, Charler ML, Papadopoulos A, Wessely S, Chalder T, Cleare AJ
Payne P, Crane-Godreau MA
