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Life span extension by targeting a link between metabolism and histone acetylation in Drosophila

The reductive potential of NADPH is maintained by glucose-6-phosphate dehydrogenase in the pentose phosphate pathway [26]

Depletion of arginine results in reduced expression of CD3, an essential part of the T cell receptor (TCR) complex, ultimately impairing T cell activation [54, 55]

Sinefungin was more potent than DZnep, causing a dose-dependent period lengthening of a much greater magnitude (Fig
