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GSH depletion is necessary for the formation of the apoptosome [124] and also triggers cell death by modulation of the permeability transition pore of the mitochondria and the activation of executioner caspases [125,126]

10.1016/j.yexcr.2021.112552 163 WangH.HeY.SunZ.RenS.LiuM.WangG.et al (2022a)

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L-Glutathione exists in two main forms: reduced glutathione (GSH) and oxidized glutathione (GSSG)

In rodent models of T1D (non-obese diabetic (NOD) mouse and biobreeding rat (BBR)), exposure to specific bacterial strains or metabolic products as well as vivarium hygiene can modulate T1D incidence [189199]