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We split each species atlas into glial cells and neurons, mapped rat and macaque genes to mouse orthologues and integrated across species

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Unlike GLP-1 agonists such as semaglutide or tirzepatide, which work primarily through appetite suppression, AOD-9604 directly enhances fat metabolism at the cellular level through beta-3 adrenergic receptor modulation

Main Research Findings 1) The findings of the study suggest that Dihexa may have the potential to treat disorders, such as Alzheimers disease, that may benefit from the augmentation of synaptic connectivity

[DOI] [PubMed] [Google Scholar] 30.Ott J, KAUfmann U, Bentz E-K, Huber J-C, Tempfer C-B