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2 Nitric oxide signaling networks in colorectal cancer In CRC, NO signaling has been implicated in multiple aspects of tumorigenesis, including tumor initiation, progression, metastasis, immune evasion, and therapeutic resistance (Figure 1

In the mammalian retina, NF-B signaling promotes glial reactivity and inhibits glia-mediated neuronal regeneration (66)

While Keap-1 acts as the inhibitor of Nrf-2 and controls its stability

The honest caveats are equally important

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