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In the TME, CD4-positive cells were almost exclusively CD3 + TCR + , confirming their T cell identity (Supplementary Fig
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Morphologic features can be appreciated better in bleached sections
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Furthermore, AGE triggered myocardial fibrosis via activation of the TGF-/Smad signaling pathway which can be blocked by AGE antibodies and SB431542 (a potent TGF-/Smad signaling pathway inhibitor) [106]
