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They are simply different routes

Evidence-Based Complementary and Alternative Medicine 2019(1):3239649 [DOI] [PMC free article] [PubMed] [Google Scholar] Kim S-M, Kim S-C, Chung I-K, Cheon W-H, Ku S-K (2012) Antioxidant and protective effects of Bupleurum falcatum on the L-thyroxine-induced hyperthyroidism in rats

There are no safety data for the proposed SC route

GSDMB (ORMDL3) and moldrelated asthma: Variants in the GSDMB/ORMDL3 locus are among the strongest common genetic risk factors for childhood asthma, and this region is highly expressed in bronchial epithelium

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