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Detection and in vitro metabolism of AOD9604

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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Nature Medicine, 25(11), 17611771

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2019) characterised 5-amino-1MQ in 3T3-L1 adipocyte research systems, where substrate-site NNMT inhibition altered cellular lipogenic gene expression profiles and adipocyte bioenergetic endpoints