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Description
If that methionine residue plays a role in receptor binding or biological activity, oxidation can reduce or eliminate the peptide effect entirely

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Whilst it is generally deemed a genetic condition in dogs (specific to certain breeds), in human studies, low levels of B12 have been associated with the condition
Characterizes copper tripeptide antioxidant and matrix metalloproteinase modulation activity

Specifically, TAM can be an estrogen agonist at GPR30 (Filardo et al., 2000
