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Description
Understanding this cascade explains both why the peptide shows promise and why results vary so dramatically between individuals

In animal studies, yes

doi:10.1631/jzus.B1100329
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In Phase 1 and 2a clinical trials, once-daily subcutaneous injections of RG7697 (0.252.5 mg) for 14 days in 56 patients with T2DM and 1.8 mg of RG7697 for 12 weeks in patients with T2DM who were poorly responsive to metformin reduced body weight and improved glycemic control
