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10.1038/338158a0 191 MoN.LiZ.-Q.LiJ.CaoY.-D

Steroidal saponins from the rhizome of Polygonatum sibiricum

Whereas control women showed no hormonally-related changes in resting rCBF, those with PMDD showed decreased resting rCBF during both estradiol ( P = 0.02) and progesterone ( P = 0.0002) add-back conditions

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Concentrations of GSSG were measured by first converting oxidized glutathione to reduced glutathione with the addition of a reducing agent (5 mmol/l dithiothreitiol) and measuring this as total GSH