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Description
Within this complex synthesis process, the availability of intracellular cysteine acts as the absolute rate-limiting step, meaning the body can only produce as much glutathione as it has cysteine available

The GST enzymes help neutralize them by attaching glutathione, allowing them to be cleared from the body
PMC 4540061
[DOI] [PubMed] [Google Scholar] 128.Pasupathy S., Tavella R., Grover S., Raman B., Procter N.E.K., Du Y.T., Mahadavan G., Stafford I., Heresztyn T., Holmes A., et al

Initial changes like improved skin hydration often appear within 2-4 weeks
