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It should be contemplated as a primary therapeutic option when insomnia constitutes a significant aspect of somatic symptoms, with mirtazapine serving as a viable alternative

Wahle et al., 2023)

Patients with hypothyroidism will experience at least one of these symptoms, but often a combination of several will be present
Larazotide is a peptide designed specifically to address intestinal permeability, commonly known as leaky gut. This condition occurs when the tight junctions in the intestinal lining loosen, allowing toxins, pathogens, and undigested food particles to escape into the bloodstream

The figure below shows a simplified treatment algorithm of lupus nephritis, indicating the landmark trials that served as the basis for such immunosuppressive regimens
