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In silico prediction of xenobiotic metabolism is an important strategy to accelerate the drug discovery process, as candidate compounds often fail in clinical phases due to their poor pharmacokinetic profiles

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FOXO4-DRI is a cell-permeable senolytic peptide antagonist for inducing apoptosis in senescent cells in aging and apoptosis research from APExBIO.

Endoplasmic reticulum stress (ERS) dynamically regulates cell fate decisions within the tumor microenvironment (TME) through the PERK, IRE1, and ATF6 pathways of the unfolded protein response (UPR), forming an ERS-Death Axis interconnected with apoptosis, autophagy, pyroptosis, and ferroptosis

Brain aneurysms (also called cerebral aneurysms or intracranial aneurysms) are a weakness in a blood vessel of the brain that leads to a bubble or bulge that can rupture or bleed