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, Matsumoto H., Umaoka Y., et al
Beyond pathway inhibition, polyphenols modulate immune responses by influencing macrophage and microglial polarization, shifting from a proinflammatory M1 phenotype to an antiinflammatory M2 state, thereby enhancing the release of antiinflammatory mediators such as IL10 and arginase1 (Di Meo et al
Think of them as tiny messengers carrying instructions your cells already know how to read
