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The cannula should ideally be inserted into the distal upper limb with avoidance of flexure sites (eg cubital fossa) to reduce risk of paravenous leakage

The biology is interesting enough that ongoing research is warranted, and I'm watching the human trial literature carefully
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Moreover, activation of the SOD2/SIRT3 pathway could be a potential mechanism of reducing mitochondrial ROS and improving placental function with NR supplementation, which needs further exploration
