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Hansen M, Scheltema MJ, Sonne DP, Hansen JS, Sperling M, Rehfeld JF, et al
Notch signaling pathway The Notch signaling pathway is a protein network critical for intercellular communication, regulating cell fate decisions, proliferation, differentiation, and apoptosis
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It also promotes Th1 and Th17 responses against both intracellular and extracellular pathogens, followed by IL-10 production to limit excessive inflammation (194)
Arrows added in purple to show the direction of gene changes for key enzymes involved in this pathway following melatonin treatment
