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Hypoxia: an architect of immune dysfunction The lung TME is often hypoxic due to rapid tumor growth outpacing angiogenesis, compounded by abnormal and leaky vasculature [68]

[PubMed: 17387133] 729

Additionally, GH plays a role in boosting fat metabolism, which aids in reducing body fat and improving body composition

The sum of angiotensins 17 and 15 divided by the sum of angiotensins I, II, 17, and 15, was calculated as a unitless marker of renin-independent alternative RAAS activation (ALT-S) 33

Bagchi et al., 2018
