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Excitotoxicity is known to play a prevalent role in the pathogenesis of multiple neurodegenerative diseases, including ALS, and is intimately linked with both oxidative and nitrosative stress [65]

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Pharmacokinetics and Research-Dosing Context The pharmacokinetics of both peptides are what make a once-weekly fixed combination feasible

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These findings show how difficult it is to predict the effects, even of a protective, antioxidant enzyme, in every situation (see also [175] and references therein)