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94 Characterized by downregulated pro-apoptotic proteins (eg, Bax) and upregulated anti-apoptotic proteins (eg, Bcl-2) under hypoxia, this phenomenon reduces the Bax/Bcl-2 ratio, stabilizes mitochondrial membrane potential, and suppresses mPTP opening, apoptosome formation, and Caspase-3 activation
A golgi-targeted platinum complex plays a dual role in autophagy regulation for highly efficient cancer therapy
doi: 10.1517/17425250903107764
Widner, and C
292 The combination of galunisertib with stereotactic body radiotherapy demonstrated tolerable toxicity in a pilot study
