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As biological models age, the natural production of this hormone significantly declines, leading to symptoms associated with metabolic deceleration and decreased regenerative capacity

The transmitted fluorescence light then passes through a pinhole which blocks scattered excitation light and fluorescence light from outside the focal spot

The combination of cisplatin and RSL3 also caused a significant reduction in mean tumour size when compared with all other groups (Fig

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doi: 10.1186/S12937-025-01193-7 119
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