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Plasma long-chain acyl-carnitine species are elevated in patients with NAFLD, obesity and type 2 diabetes, suggesting that more fatty acids can enter the mitochondria, but since there is also an elevation of short-chain acyl-carnitines there might be a defect in the oxidation pathways

In the nucleus, GSH maintains the redox status of the sulfhydryl groups of the proteins involved in nucleic acid biosynthesis and DNA repair

These cells contain lymphocytes, monocytes, dendritic cells, and natural killer cells

OBoyle, N

However, adverse environmental conditions often disrupt intracellular redox homeostasis and therefore require mechanisms to balance oxidative stress