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10.1016/j.bioorg.2019.03.054 222 ZhouY.JiangZ.LuH.XuZ.TongR.ShiJ.et al (2019)

These molecules are predominantly regulated by nuclear factor-kappa B (NF-B), and mostly produced in keratinocytes, which are the predominant cell type in the epidermis [29]

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The PRP is created from a small amount of blood using a centrifuge to separate platelets from red blood cells

Thus, CHAC1s role in inducing ER stress and ferroptosis highlights its potential as a therapeutic target to increase the efficacy of DTX in treating castration-resistant prostate cancer (He et al., 2021)
